The Significance of High-Protein Total Diet Replacements in Achieving and Maintaining Healthy Weight Loss
Latest study results published in The American Journal of Clinical Nutrition suggest that high-protein total diet replacements are a promising nutritional strategy to combat the rising rate of obesity.
More calories were expended over 24 hours.
More calories expended during sleep and after the consumption of meals.
Increased fat oxidation (fat loss).
Negative fat balance: more fat was lost by participants than consumed.
High-protein total diet replacements (HP-TDR) have become increasingly popular strategies to combat obesity. They are calorie-controlled, nourishing and contain high levels of protein to promote a feeling of fullness. Research also suggests that they can increase energy expenditure and have the ability to reduce fat stores while preserving muscle mass, offering a promising strategy for healthy weight loss and weight maintenance.
The latest study- "A High-Protein Total Diet Replacement Increases Energy Expenditure and Leads to Negative Fat Balance in Healthy, Normal-Weight Adults", published in the prestigious American Journal of Clinical Nutrition compared the impact of a high-protein total diet replacement (Almased) to that of a typical North American diet (control group) by measuring energy metabolism, metabolic blood markers and appetite sensations.
The study was carried out by researchers from the University of Alberta, Canada. Consisting of forty-three healthy, normal-weight adults (19 females and 24 males) aged between 18 and 35, subjects were randomly assigned to one of the two groups- a high-protein total diet replacement group (HP-TDR) and a control group. One group consumed Almased (HP-TDR) which consisted of 35% carbohydrate, 40% protein and 25% fat. The control group consumed a calorie-equivalent diet consisting of 55% carbohydrate, 15% protein and 30% fat, typical to that of a North American diet. Participants received the prescribed diets for a 32-hour period while inside a metabolic chamber (whole-body calorimetry unit).
Figure 1: Overview of the experimental protocol (A) and variables assessed during each 32-hr test (B). CON, control diet; EE, energy expenditure; HP-TDR, high-protein total diet replacement; N/A, not applicable; REE, resting energy expenditure; WBCU, whole-body calorimetry unit.
Compared to the North American diet group, findings from the Almased meal replacement group revealed higher energy expenditure, increased fat oxidation and negative fat balance, likely implying body fat loss. The results of the study provide further evidence that a calorie is not just a calorie and that differing macronutrient compositions (high-protein, reduced carbohydrate) of diets might offer a metabolic advantage and result in greater weight loss.
In summary, the main findings of this study suggest that a high-protein total diet replacement (Almased) led to:
- More calories expended over 24 hours.
- More calories expended during sleep and after the consumption of meals.
- Increased fat oxidation (fat loss).
- Negative fat balance: more fat was lost by participants than consumed.
These first of their kind findings confirm how consuming meal replacements such as Almased results in greater daily calorie expenditure and greater fat burning when compared to a typical North American diet. Significantly, the observed negative fat balance highlights greater body fat loss when consuming a high-protein total diet replacement.
The results of this study suggest that high-protein total diet replacements may be a promising nutritional strategy for achieving and maintaining weight loss and ultimately combating the rising rates of obesity.
What is Almased?
Almased, Germany's No.1 meal replacement is a high-protein, low glycaemic index formula. It is supported by over 30 years of scientific research and contains a natural, nourishing blend of soya, yogurt and enzyme-rich honey with added vitamins and minerals. Almased is a powder mix, which can be added to water or low-fat milk. It can be used to replace any daily meal.
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Almased is available to purchase from Boots, Lloyds and Amazon.
To read the full study, click here.
Study reference: Oliveira, C et al (2020). A high-protein total diet replacement increases energy expenditure and leads to negative fat balance in normal-weight adults. American Journal of Clinical Nutrition.
19. November 2020